Application of a hot-melt granulation process to enhance fenofibrate solid dose manufacturing.
Drug Dev Ind Pharm. 2016;42(7):1137-48. doi: 10.3109/03639045.2015.1117484. Epub 2015 Dec 7. Chaudhary RS1, Amankwaa E1, Kumar S1, Hu T1, Chan M1, Sanghvi P1. Author information 1a Apotex Inc. , Toronto , ON , Canada. Abstract Evaluation of hot-melt granulation of fenofibrate and croscarmellose sodium and its cooling time for the molten mass in a ratio of 55:45 was conducted to assess the manufacturing […]